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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-133b
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs)
Methods transfection, qRT-PCR, Western blot, immunocytochemical assay, MTT assay, APC/7‑AAD staining, luciferase reporter assay
Expression pattern associated
Functional description Overexpression of miR-133b inhibited the proliferation and promoted apoptosis in a DR cell model by downregulating RhoA expression.
PubMed ID 29786744
Year 2018
Title miR‑133b regulates proliferation and apoptosis in high‑glucose‑induced human retinal endothelial cells by targeting ras homolog family member A.
Drug-related ncRNA NO

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